Associate Scientist, Viral Vector Production - Cell Therapy

Sonoma BioTherapeutics

Sonoma BioTherapeutics

Seattle, WA, USA
Posted on Saturday, August 12, 2023

About Sonoma Biotherapeutics:

Sonoma Biotherapeutics is a South San Francisco and Seattle-based company leading the development of adoptive Treg therapies cell for autoimmune and degenerative diseases. Using next-generation genome editing and target-specific cell therapy, Sonoma is focused on developing its best-in-class platform across the entire spectrum of Treg cell therapeutic capabilities. Founded by pioneers in Treg biology and cell therapy, the company brings together leading expertise and proprietary methodologies for the discovery and development of disease modifying and curative therapies. More information at www.sonomabio.com.

Job Purpose/Summary:

We are seeking a motivated research associate scientist to join the viral vector production team at Sonoma Biotherapeutics in Seattle. This role will perform viral production, run titer analysis, and test potential process and analytical improvements; working closely with the manager and team to ensure timely high-quality viral vector production in support of Sonoma’s research programs. The successful candidate will be expected to master aseptic mammalian cell culture techniques, plasmid transfection, flow cytometry, and molecular quantitation. The ideal candidate will demonstrate willingness and ability to learn and apply skills to accomplish tasks and possess reliability and adaptability to team-oriented work.

Roles and responsibilities:

  • Produce high quality engineered viruses such as LV and AAV for Sonoma non-clinical projects
  • Perform functional titer and molecular quantitation assays (qPCR and ddPCR)
  • Execute established SOPs and maintain accurate and detailed documentation in electronic lab notebook
  • Coordinate and communicate with supervisor and colleagues to adhere to on-time production and delivery schedule
  • Ability to perform tasks reliably and independently in timely manner
  • Contribute to development and optimization efforts to improve production process and viral purity and titer
  • Maintain viral core laboratory supplies, stocks, and operations to ensure a functional lab environment
  • Comply to all lab safety procedures and practices
  • Contribute to the collaborative, helping, and fun Sonoma culture
  • Other operation-related duties may be assigned

Qualifications and Education Requirements:

  • BS in Molecular Cell Biology, Virology, Immunology, Bioengineering or related life science field
  • 1-3 years of laboratory experience in aseptic mammalian cell culture and biological/molecular biological assays
  • Proficient with MS Office and other commonly used technology software
  • Effective verbal and written communication skills to proactively report and discuss results with manager and team
  • Ability to learn and adapt quickly, utilize critical thinking, and thrive in a team-oriented and fast-paced environment
  • Attention to detail with strong organization skills
  • All-star work ethic (self-driven, accountable, can-do attitude, and good lab citizen)

Preferred Skills:

  • Experience in working in a BSL-2 environment
  • Experience with cell transfection
  • Experience with flow cytometry
  • Familiarity with molecular biology techniques and analysis (DNA/RNA extraction, qPCR, ddPCR)

Other duties:

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities, and activities may change at any time with or without notice.

Equal Employment Opportunity

At Sonoma Biotherapeutics, we believe that the highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other. We are committed to building an open, diverse, and inclusive culture for all employees.

Sonoma Biotherapeutics is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status or any other characteristics protected under applicable federal, state and local laws.