Locations
San Francisco, CA, USA · South San Francisco, CA, USA
industry
Biotechnology
Size
1 - 10 employees
Stage
Seed
founded in
2014
Serotiny is a therapeutic discovery company that designs new genes for next generation cell and gene therapies. We invent therapeutic multi-domain proteins in high-throughput by orchestrating software, mammalian synthetic biology, and therapeutic expertise. At the heart of Serotiny’s technology is a discovery platform involving the close interworking of computationally aided protein design, high-throughput cellular assays, and sophisticated data-driven analytics, which together enable Serotiny to engineer multi-domain proteins for cell therapies, like chimeric antigen receptors used in CAR-T immunotherapies and second-generation Cas9-based gene editing tools, like base and prime editors. Rationally designing proteins for cell and gene therapies requires a different set of constraints and design tools than enzyme or antibody engineering. These therapeutic multi-domain proteins will not be purified; they will be expressed in a human cell, and they will affect the therapeutic phenotype.
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